Artrilen

Bioactive Composition and Mechanisms of Action

Phytotherapeutic Extracts of Clinical Relevance

• Devil’s Claw (Harpagophytum procumbens) – Dry extract titrated to 2.5% Harpagosides:
  Traditionally used in South African medicine, it is known for its analgesic and anti-inflammatory properties.
  Preclinical studies have shown a key role in COX-2 modulation, helping to reduce joint pain and inflammation.

• Boswellia Serrata – Dry extract titrated to 95% Boswellic Acids:
  Boswellic acids are well-documented for their ability to inhibit 5-lipoxygenase, thereby reducing chronic inflammation.
  In addition to joint support, benefits have also been observed for gastrointestinal and respiratory function.

• Curcuma Longa – Rhizome extract titrated to 95% Curcuminoids:
  Recognized as one of the most potent natural anti-inflammatory agents, curcuminoids modulate molecular pathways such as NF-κB, offering protection against oxidative stress and improving joint and liver function.

• Ashwagandha (Withania somnifera) – Dry extract:
  This adaptogenic plant enhances both physical and mental endurance, reduces the effects of chronic stress, and supports tissue recovery.

Synergistic Bioactive Compounds

• Glucosamine Sulfate:
  Acts as a precursor in the synthesis of glycosaminoglycans and proteoglycans, essential for maintaining the cartilage matrix.
  It also stimulates the production of hyaluronic acid, improving the viscoelastic properties of synovial fluid.

• Chondroitin Sulfate:
  Helps reduce joint pain and slow cartilage degeneration, as demonstrated in osteoarthritis models.

• MSM (Methylsulfonylmethane):
  A bioavailable source of sulfur, crucial for cartilage biosynthesis.
  It exhibits anti-inflammatory and antioxidant properties, alleviating chronic joint pain.

• Type II Collagen:
  The main structural component of articular cartilage, Type II collagen helps preserve structural integrity and functional elasticity, promoting mechanical resilience of the joints.

Antioxidant Support and Essential Cofactors

• Vitamin C (Ascorbic Acid):
  A key cofactor in collagen synthesis, it protects cells from free radical damage and contributes to maintaining the structural integrity of connective tissue.

Clinical Evidence and Nutritional Synergies

The combination of plant extracts and bioactive compounds in Artrilen is designed to deliver a multifunctional intervention.
This advanced formulation:

• Reduces chronic inflammatory processes and joint pain;

• Promotes cartilage matrix regeneration;

• Enhances joint lubrication and mechanical resilience;

• Provides antioxidant protection against systemic oxidative stress;

• Supports physiological adaptation to chronic joint stress conditions.

Dosage and Directions for Use

Take 1 tablet per day, preferably with meals, to ensure optimal absorption of liposoluble active ingredients.

Warnings Do not exceed the recommended daily dose.
Consult your healthcare professional before use if you are pregnant, breastfeeding, or taking any medication.